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Cytochrome P450 enzymes

Showing 1 - 25 of 3,937
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Healthy Trial in Geneva (Dextromethorphan 5 MG, Paroxetine 10Mg Tablet, Paroxetine 20Mg Tablet)

Completed
  • Healthy
  • Dextromethorphan 5 MG
  • +2 more
  • Geneva, Switzerland
    HUG
Jan 3, 2022

Tuberculosis Trial in Cape Town (phenotyping cocktail, rifampicin)

Completed
  • Tuberculosis
  • Cape Town, South Africa
  • +1 more
Aug 16, 2021

Macrophage Function

Enrolling by invitation
  • Polymorphism
  • Lung Inflammation
    • Research Triangle Park, North Carolina
      NIEHS, Research Triangle Park
    Jul 6, 2022

    Drug-Interactions Trial in Baltimore (Inje cocktail, THC Cannabis extract, THC/CBD Cannabis Extract)

    Active, not recruiting
    • Drug-Interactions
    • Inje cocktail
    • +2 more
    • Baltimore, Maryland
      Johns Hopkins University
    Mar 21, 2022

    Chronic Myeloid Leukemia, Chronic Phase Trial in Monterrey (Dasatinib Pill, Ketoconazole Pill)

    Recruiting
    • Chronic Myeloid Leukemia, Chronic Phase
    • Dasatinib Pill
    • Ketoconazole Pill
    • Monterrey, Nuevo Leon, Mexico
      Hospital Universitario Dr. José Eleuterio González
    Nov 25, 2022

    Antipsychotic Induced Weight Gain, Non-alcoholic Steatohepatitis (NASH) Trial in Miami (Miricorilant, Fluvoxamine)

    Recruiting
    • Antipsychotic Induced Weight Gain
    • Non-alcoholic Steatohepatitis (NASH)
    • Miami, Florida
      Site 01
    Feb 3, 2023

    Atopic Dermatitis Trial (Caffeine, Metoprolol, Midazolam)

    Not yet recruiting
    • Atopic Dermatitis
    • Caffeine
    • +6 more
    • (no location specified)
    May 26, 2023

    Parkinson Disease Trial in Madison (Tavapadon, Carbamazepine)

    Active, not recruiting
    • Parkinson Disease
    • Madison, Wisconsin
      Madison, Wisconsin
    Jan 13, 2023

    HIV Trial in Baltimore (VH4524184, Midazolam, Placebo)

    Recruiting
    • HIV Infections
    • Baltimore, Maryland
      GSK Investigational Site
    Jan 11, 2023

    Atopic Dermatitis Trial in Bulgaria, United States (Nemolizumab, CYP 450 Substrates)

    Recruiting
    • Atopic Dermatitis
    • North Hollywood, California
    • +6 more
    Nov 29, 2022

    Ulcerative Colitis (UC), Crohn's Disease Trial in Germany, Israel, United States (Risankizumab, Cytochrome P450 (CYP)

    Completed
    • Ulcerative Colitis (UC)
    • Crohn's Disease
    • Coronado, California
    • +5 more
    Oct 20, 2022

    Healthy Volunteer Trial in London (CC-99677, Methotrexate, Sulfasalazine)

    Completed
    • Healthy Volunteer
    • London, United Kingdom
      Richmond Pharmacology Limited
    Aug 17, 2021

    AOD Effects and Consequences Trial in Cologne (caffeine, tolbutamide, omeprazole, dextromethorphan, digoxin, midazolam single

    Completed
    • AOD Effects and Consequences
    • caffeine, tolbutamide, omeprazole, dextromethorphan, digoxin, midazolam single doses
    • ethanol multiple doses plus caffeine, tolbutamide, omeprazole, dextromethorphan, digoxin, midazolam single doses
    • Cologne, NRW, Germany
      Department of Pharmacology I, University Hospital Cologne
    Sep 6, 2019

    Drug-drug Interactions Trial in DeLand (napabucasin, cytochrome P450 (CYP450) probe drugs or BCRP transporter substrate)

    Completed
    • Drug-drug Interactions
    • napabucasin
    • cytochrome P450 (CYP450) probe drugs or BCRP transporter substrate
    • DeLand, Florida
      Accel Research Sites
    Apr 4, 2022

    Healthy Volunteers, Overweight, Obesity Trial in San Antonio (NNC9204-1177, Cocktail of 5 already approved drugs)

    Completed
    • Healthy Volunteers
    • +2 more
    • San Antonio, Texas
      Novo Nordisk Investigational Site
    Jan 20, 2020

    Human Immunodeficiency Virus Type 1 (HIV-1) Infection Trial (Vesatolimod, Cobicistat, Voriconazole)

    Not yet recruiting
    • Human Immunodeficiency Virus Type 1 (HIV-1) Infection
    • (no location specified)
    Jul 11, 2022

    Crohn Disease, Ulcerative Colitis Trial in Worldwide (Ustekinumab IV Infusion, Ustekinumab SC Injection, Midazolam 2 mg)

    Suspended
    • Crohn Disease
    • Ulcerative Colitis
    • Ustekinumab IV Infusion
    • +7 more
    • Cypress, California
    • +15 more
    Jul 21, 2022

    Healthy Trial in Salt Lake City (BMS-986165, Fluvoxamine)

    Completed
    • Healthy
    • Salt Lake City, Utah
      ICON Plc (PRA Health Sciences)
    Nov 9, 2021

    Liver Cirrhosis Trial (Caffeine, Warfarin sodium, Omeprazole)

    Not yet recruiting
    • Liver Cirrhosis
    • (no location specified)
    Feb 14, 2023

    Drug Intolerance, Cytochrome P450 CYP2D6 Enzyme Deficiency, Drug Effect Trial in Geneva (Pupillometry)

    Terminated
    • Drug Intolerance
    • +2 more
    • Pupillometry
    • Geneva, Switzerland
      Geneva University Hospitals, Geneva, Switzerland
    Nov 24, 2022

    Healthy Trial in Rennes (Drug Cocktail, Foliglurax, midazolam iv)

    Completed
    • Healthy
    • Drug Cocktail
    • +2 more
    • Rennes, France
      Biotrial
    Apr 22, 2020

    Healthy Volunteers Trial in Berlin (Zoliflodacin Patheon)

    Recruiting
    • Healthy Volunteers
    • Zoliflodacin Patheon
    • Berlin, Germany
      Parexel Early Phase Clinical Unit
    Nov 22, 2022

    Healthy Participants Trial in Dallas (MYK-224, Itraconazole, Verapamil)

    Recruiting
    • Healthy Participants
    • Dallas, Texas
      Labcorp CRU
    Jun 9, 2022

    Cytochrome P450 Abnormalities in Patients With Delirium.

    Completed
    • Delirium, Cytochrome P-450 Enzyme System
    • Cytochrome P450 test
    • Park Ridge, Illinois
      David Ronin
    Jul 14, 2020

    Pharmacologic Action Trial in Silver Spring (Primaquine)

    Completed
    • Pharmacologic Action
    • Silver Spring, Maryland
      WRAIR
    Oct 18, 2021